Poly(N-vinylpyrrolidone)-block-poly(d,l-lactide) as a new polymeric solubilizer for hydrophobic anticancer drugs: in vitro and in vivo evaluation
Poly(N-vinylpyrrolidone)-block-poly(d,l-lactide) as a new polymeric solubilizer for hydrophobic anticancer drugs: in vitro and in vivo evaluation ~ Nonionic, low-molecular weight surfactants are widely used as parenteral formulation vehicles to solubilize hydrophobic anticancer drugs. For example, taxane and podophyllotoxin derivative solutions for intravenous (i.v.) administration are formulated with polyethoxylated castor oil (CremophorR EL, CrmEL) or polysorbate [...]
November 01, 2012 | Posted in : Cancer | There’s no comment yet | » read more . . .
Development of anticancer drugs targeting the MAP kinase pathway
Development of anticancer drugs targeting the MAP kinase pathway ~ Many receptor tyrosine kinases and cytokine receptors in association with heterotrimeric G proteins are known to activate intracellular protein serine/threonine kinases termed mitogen-activated protein kinases (MAPKs). Of the various families of MAPKs, which are also referred to as extracellular signal-regulated kinases (ERKs), the first to [...]
November 01, 2012 | Posted in : Cancer | There’s no comment yet | » read more . . .
Positive Psychology, Positive Prevention, and Positive Therapy
Positive Psychology, Positive Prevention, and Positive Therapy ~ Psychology after World War II became a science largely devoted to healing. It concentrated on repairing damage using a disease model of human functioning. This almost exclusive attention to pathology neglected the idea of a fulfilled individual and a thriving community, and it neglected the possibility that [...]
October 31, 2012 | Posted in : Psychiatric and Psychology | There’s no comment yet | » read more . . .
Hearing, Its Psychology and Physiology
Hearing, Its Psychology and Physiology ~ Hearing: Its Psychology and Physiology was written in 1936-37 at a time when psychoacoustics had matured but auditory biophysics ad electrophysiology were still adolescent. Modern techniques for generating and measuring sound had been developed in the 1920s and they had been applied to the description of human auditory abilities. [...]
October 31, 2012 | Posted in : Psychiatric and Psychology | There’s no comment yet | » read more . . .
The Psychology Of Happiness
The Psychology Of Happiness ~ It seems everyone has a view on happiness. Joan Collins, the Dalai Lama and over 100 others have released new titles on the subject since the beginning of 2001. Michael Argyle takes a different approach to most. In his text, The Psychology of Happiness, he examines what science can tell [...]
October 31, 2012 | Posted in : Psychiatric and Psychology | There’s no comment yet | » read more . . .
The Psychology of Written Composition
The Psychology of Written Composition ~ The mental activities of writing considered in our research are the same kinds of higher mental processes that figure in cognitive research on all aspects of human intelligence. They include goal setting, planning, memory search, problem solving, evaluation, and diagnosis. Writing is, of course, easily recognized as an activity [...]
October 31, 2012 | Posted in : Psychiatric and Psychology | There’s no comment yet | » read more . . .
Principles Of Gestalt Psychology
Principles Of Gestalt Psychology ~ When I first conceived the plan of writing this book I guessed, though I did not know, how much effort it would cost to carry it out, and what demands it would put on a potential reader. And I doubted, not rhetorically but very honestly and sincerely, whether such labour [...]
October 31, 2012 | Posted in : Psychiatric and Psychology | There’s no comment yet | » read more . . .
Organizational Psychology
Organizational Psychology ~ With books on organizations written these days by authors ranging from athletes to Eastern mystics, it is worthwhile revisiting one of the classics of organizational psychology. With the macro shifts in the global economy and extraordinary advancements in the digital infrastructure, there is a temptation by managers to dismiss Edgar Schein’s Organizational [...]
October 31, 2012 | Posted in : Psychiatric and Psychology | There’s no comment yet | » read more . . .
The Social Psychology Of Organisations
The Social Psychology Of Organisations ~ Past approaches to the study of social problems and social behaviour have been limited by a lack of adequate conceptual tools. This limitation has been manifest both in psychology and sociology, although in different ways. Psychologists have been characteristically unable or willing to deal with the fact of social [...]
October 31, 2012 | Posted in : Psychiatric and Psychology | There’s no comment yet | » read more . . .
Studying Quantitative Methods at Vanderbilt An Introduction for Graduate Students in Education and Psychology
Studying Quantitative Methods at Vanderbilt An Introduction for Graduate Students in Education and Psychology ~ Training in quantitative methods is a key component of education in Education and the Psychological Sciences at Vanderbilt. During your first year, you will take at least one quantitative methods course, and probably two. Currently, there are two primary course [...]
October 31, 2012 | Posted in : Psychiatric and Psychology | There’s no comment yet | » read more . . .
Risks of High-Dose Stimulants in the Treatment of Disorders of Excessive Somnolence: A Case-Control Study
Risks of High-Dose Stimulants in the Treatment of Disorders of Excessive Somnolence: A Case-Control Study ~ A few studies of acute cardiovascular complications of these drugs have been reported. Recreational use of stimulants has been associated with both hemorrhagic and ischemic stroke, but with an unclear relation to drug dose.2,3 One case report described a [...]
October 31, 2012 | Posted in : Medicine | There’s no comment yet | » read more . . .
Treating Fibromyalgia With a Brief Interdisciplinary Program: Initial Outcomes and Predictors of Response
Treating Fibromyalgia With a Brief Interdisciplinary Program: Initial Outcomes and Predictors of Response ~ Fibromyalgia is a chronic disorder characterized by diffuse pain, stiffness, and fatigue.1 The 1990 American College of Rheumatology criteria for diagnosing fibromyalgia are widespread pain and tenderness at 11 of 18 specific tender points. These criteria have a sensitivity of 88% [...]
October 31, 2012 | Posted in : Psychiatric and Psychology | There’s no comment yet | » read more . . .
