Natural Products in Drug Discovery and Development
Natural Products in Drug Discovery and Development ~ Analysis of the number and sources of anticancer and antiinfective agents, reported mainly in Annual Reports of Medicinal Chemistry from 1984 to 1995, indicates that over 60% of the approved drugs and pre-NDA candidates (for the period 1989-1995), excluding biologics, developed in ...
November 01, 2012 by Jimbo | Cancer | photos | » read more . . .
Development of anticancer drugs targeting the MAP kinase pathway
Development of anticancer drugs targeting the MAP kinase pathway ~ Many receptor tyrosine kinases and cytokine receptors in association with heterotrimeric G proteins are known to activate intracellular protein serine/threonine kinases termed mitogen-activated protein kinases (MAPKs). Of the various families of MAPKs, which are also referred to as extracellular signal-regulated ...
November 01, 2012 by Jimbo | Cancer | photos | » read more . . .
Poly(N-vinylpyrrolidone)-block-poly(d,l-lactide) as a new polymeric solubilizer for hydrophobic anticancer drugs: in vitro and in vivo evaluation
Poly(N-vinylpyrrolidone)-block-poly(d,l-lactide) as a new polymeric solubilizer for hydrophobic anticancer drugs: in vitro and in vivo evaluation ~ Nonionic, low-molecular weight surfactants are widely used as parenteral formulation vehicles to solubilize hydrophobic anticancer drugs. For example, taxane and podophyllotoxin derivative solutions for intravenous (i.v.) administration are formulated with polyethoxylated castor oil ...
November 01, 2012 by Jimbo | Cancer | photos | » read more . . .
Acupuncture Point Topography in the Horse
Christiane P. Krueger, D. V. M. Tannenstrasse 6, D 8431 Freystadt/Opf., West Germany Abstract: Chinese texts describe some 130 acu- puncture points on the horse, but fail to identify the “master points” and their locations. This lack of clearness was the reason for a more precise examination of the acupuncture points and their ...
February 07, 2013 by densus99 | Medicine | photos | » read more . . .
Chinese acupuncture–moxibustion
Chinese acupuncture–moxibustion75Chinese medicine (TCM). It is the study ofthe meridians and collaterals, acupoints,acupuncture techniques, and the laws ofprevention and treatment of diseases byacupuncture–moxibustion. Thousands ofyears ago, ancient Chinese medicine usedbianstone (needle stone) as an instrumentfor the treatment of diseases, and thendiscovered the points and invented specialacupuncture instruments. Gradually, the“theory of ...
February 07, 2013 by densus99 | Health & Medicine | photos | » read more . . .
Somatosympathetic Reflex and Acupuncture-Related Analgesia
Corresponding author: Dr. Yuan-Feen Tsai, Department of Physiology, College of Medicine, National Taiwan University, No. 1 Jen-Ai Road, Section 1, Taipei 10051, Taiwan, ROC. Tel: +886-2-2312-3456 ext. 88240, Fax: +886-2-2322-5007, E-mail:
[email protected] Received: June 19, 2009; Accepted: August 17, 2009. ©2009 by The Chinese Physiological Society. ISSN : 0304-4920. http://www.cps.org.tw ...
February 07, 2013 by densus99 | Medicine | photos | » read more . . .
Clinical Research on Treating Senile Dementia by Combining Acupuncture with Acupoint-Injection
Yemeng Chen, M.D. Acupuncture Department, Huashan Hospital Shanghai Medical University, Shanghai 20040, P. R. China Abstract: Combining: Combining acupuncture with acupoint-injection of aceglutamidi has been used in treating 38 cases of senile dementia. The experiment showed that the therapy is effective for the cases of multi-infarct dementia, the rate of success being 42.82% ...
February 07, 2013 by densus99 | Medicine | photos | » read more . . .
Acupuncture and Knee Osteoarthritis A Three-Armed Randomized Trial
Acupuncture and Knee Osteoarthritis A Three-Armed Randomized Trial Hanns-Peter Scharf, MD; Ulrich Mansmann, PhD; Konrad Streitberger, MD; Steffen Witte, PhD; Jürgen Krämer, MD; Christoph Maier, MD; Hans-Joachim Trampisch, PhD; and Norbert Victor, PhD Background: Despite the popularity of acupuncture, evidence of its efficacy for reducing pain remains equivocal. Objective: To assess the efficacy and ...
February 07, 2013 by densus99 | Medicine | photos | » read more . . .
Effects of Acupuncture at Neiguan (PC 6) of thePericardial Meridian on Blood Pressure and Heart Rate Variability
Corresponding author: Dr. Shyang Chang, Department of Electrical Engineering, National Tsing Hua University, Hsinchu, Taiwan 300, ROC. Tel: 886-35731146, Fax: 886-35715971, E-mail:
[email protected] Received: October 8, 2007; Revised: December 27, 2007; Accepted: February 19, 2008. 2008 by The Chinese Physiological Society. ISSN : 0304-4920. http://www.cps.org.tw Chinese Journal of Physiology 51(3): ...
February 07, 2013 by densus99 | Medicine | photos | » read more . . .
Effect of electro-acupuncture at Foot-Yangming Meridian onsomatostatin and expression of somatostatin receptor genesin rabbits with gastric ulcer
Shou-Xiang Yi, Ren-Da Yang, Jie Yan, Xiao-Rong Chang, Ya-Ping Ling www.wjgnet.com Shou-Xiang Yi, Ren-Da Yang, Jie Yan, Xiao-Rong Chang, Ya- Ping Ling, Department of Acupuncture and Moxibustion, Hunan College of Traditional Chinese Medicine, Changsha 41007, Hunan Province, China Supported by the National Natural Science Foundation of China, No.30171136 Correspondence to: Professor Shou-Xiang ...
February 07, 2013 by densus99 | Medicine | photos | » read more . . .
A pilot study on acupuncture for lower urinary tract symptomsrelated to chronic prostatitis/ chronic pelvic pain
Research A pilot study on acupuncture for lower urinary tract symptoms related to chronic prostatitis/chronic pelvic pain Jillian L Capodice*1, Zhezhen Jin2, Debra L Bemis1, David Samadi1, Brian A Stone1, Steven Kapan3 and Aaron E Katz1 Address: 1Department of Urology, Columbia University Medical Center, New York, NY 10032, USA, 2Department of Biostatistics, Columbia University Medical ...
February 07, 2013 by densus99 | Medicine | photos | » read more . . .
